Selective Estrogen Receptor Modulators PDF
By:Andrea Manni,Michael Verderame
Published on 2002-01-18 by Springer Science & Business Media
Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.
This Book was ranked at 26 by Google Books for keyword Sexual Health Sexual Health Impotence novel.
Book ID of Selective Estrogen Receptor Modulators's Books is -XTOBgAAQBAJ, Book which was written byAndrea Manni,Michael Verderamehave ETAG "NIYd4E7/IEI"
Book which was published by Springer Science & Business Media since 2002-01-18 have ISBNs, ISBN 13 Code is 9781592591572 and ISBN 10 Code is 1592591574
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Book which have "374 Pages" is Printed at BOOK under CategoryMedical
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